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Is Histone acetylation associated with higher or lower gene expression normally?
also, can you explain why.
1 Comment. Posted by admin on Sunday, June 28, 2009 at 1:18 pm.
Filed under Homework Help, Gene Expression, Science Question.
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Higher…. histone acetylation removes the positive charge at the N terminus of the histone protein.. this causes means that the affinity of histone with DNA is reduced… Hence, this makes it easier for DNA pol III and other transcription factors to accsess promotor sites to synthesis RNA… which will cause more RNA to be produced….
Hope that helps
June 28th, 2009 at 5:11 pm